The Salience Network

The Salience network is made up of the anterior cingulate cortex and the insula.  Together they coordinate to monitor the conditions in the body for homeostasis (insula) from temperature, to pH, to pain, to hormonal discomfort and notify the anterior cingulate cortex.  You may recall that the ACC handles conflict.  Well, those would be the conflicts.  Also keep in mind that information coming in through the senses, including auditory, visual, and tactile are part of the data integrated by the insula.

Once the salience network is activated it modulates the default mode network.  It kicks the brain out of daydreaming, mind wandering,  and other self-referential behavior and into ready for action mode.


Neurohypnotic bonus

  1. A critical role for the right fronto-insular cortex in switching between central-executive and default-mode networks
  2. Inside a Brain Circuit, the Will to Press On

  3. Modulatory interactions between the default mode network and task positive networks in resting-state

  4. Saliency, switching, attention and control: a network model of insula function
  5. Salience network integrity predicts default mode network function after traumatic brain injury
  6. Dissociable Intrinsic Connectivity Networks for Salience Processing and Executive Control

  7. Shifted intrinsic connectivity of central executive and salience network in borderline personality disorder